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Intracellular Context Affects Levels of a Chemically Dependent Destabilizing Domain

The ability to regulate protein levels in live cells is crucial to understanding protein function. In the interest of advancing the tool set for protein perturbation, we developed a protein destabilizing domain (DD) that can confer its instability to a fused protein of interest. This destabilization...

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Detalles Bibliográficos
Main Authors: Sellmyer, Mark A., Chen, Ling-chun, Egeler, Emily L., Rakhit, Rishi, Wandless, Thomas J.
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2012
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3440426/
https://ncbi.nlm.nih.gov/pubmed/22984418
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0043297
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