Myelin-Derived Lipids Modulate Macrophage Activity by Liver X Receptor Activation

Multiple sclerosis is a chronic, inflammatory, demyelinating disease of the central nervous system in which macrophages and microglia play a central role. Foamy macrophages and microglia, containing degenerated myelin, are abundantly found in active multiple sclerosis lesions. Recent studies have de...

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Bibliographic Details
Main Authors: Bogie, Jeroen F. J., Timmermans, Silke, Huynh-Thu, Vân Anh, Irrthum, Alexandre, Smeets, Hubert J. M., Gustafsson, Jan-Åke, Steffensen, Knut R., Mulder, Monique, Stinissen, Piet, Hellings, Niels, Hendriks, Jerome J. A.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2012
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3440367/
https://ncbi.nlm.nih.gov/pubmed/22984598
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0044998
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