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Conformation dependent binding of netropsin and distamycin to DNA and DNA model polymers

The binding of the antibiotics netropsin and distamycin A to DNA has been studied by thermal melting, CD and sedimentation analysis. Netropsin binds strongly at antibiotic/nucleotide ratios up to at least 0.05. CD spectra obtained using DNA model polymers reveal that netropsin binds tightly to poly...

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Bibliografiske detaljer
Udgivet i:Nucleic Acids Res
Principais autores: Luck, G., Triebel, H., Waring, M., Zimmer, Ch.
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 1974
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC344032/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10793682/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/1.3.503
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