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Conformation dependent binding of netropsin and distamycin to DNA and DNA model polymers
The binding of the antibiotics netropsin and distamycin A to DNA has been studied by thermal melting, CD and sedimentation analysis. Netropsin binds strongly at antibiotic/nucleotide ratios up to at least 0.05. CD spectra obtained using DNA model polymers reveal that netropsin binds tightly to poly...
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| Autores principales: | , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
1974
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| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC344032/ https://ncbi.nlm.nih.gov/pubmed/10793682 |
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