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Conformation dependent binding of netropsin and distamycin to DNA and DNA model polymers

The binding of the antibiotics netropsin and distamycin A to DNA has been studied by thermal melting, CD and sedimentation analysis. Netropsin binds strongly at antibiotic/nucleotide ratios up to at least 0.05. CD spectra obtained using DNA model polymers reveal that netropsin binds tightly to poly...

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Bibliografiska uppgifter
Huvudupphovsmän: Luck, G., Triebel, H., Waring, M., Zimmer, Ch.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 1974
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC344032/
https://ncbi.nlm.nih.gov/pubmed/10793682
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