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Protection of (dA.dT) cluster regions in the DNAase I cleavage of DNA by specific interaction with netropsin.

The specific DNA binding ligand netropsin selectively blocks dA-dT base pairs in clusters containing two or more consecutive thymine residues at the dNAase I cleavage sites of DNA. Using CD and UV absorption measurements it is shown, that at various ratios of netropsin to nucleotide concentrations a...

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Détails bibliographiques
Auteurs principaux: Zimmer, C, Luck, G, Nüske, R
Format: Artigo
Langue:Inglês
Publié: 1980
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC324140/
https://ncbi.nlm.nih.gov/pubmed/6253900
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