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Oncoprotein Cot1 Represses Kinase Suppressors of Ras1/2 and 1,25-Dihydroxyvitamin D(3)-Induced Differentiation of Human Acute Myeloid Leukemia Cells

Metabolites and derivatives of vitamin D are well-known inducers of monocytic differentiation, but the mechanistic basis for their action is not fully elucidated. Here we show that the product of protooncogene Cot1 represses the monocytic phenotype in human acute myeloid leukemia (AML) cells induced...

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Hlavní autoři: WANG, XUENING, STUDZINSKI, GEORGE P.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3440184/
https://ncbi.nlm.nih.gov/pubmed/20945381
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcp.22449
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