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Total Synthesis of Theopederin D

The total synthesis of the potent cytotoxin theopederin D has been achieved through the use of an oxidative carbon–carbon bond cleavage reaction to form an acyliminium ion in the presence of acid labile acetal groups Other key transformations include an acid mediated functionalization of a tetrahydr...

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Detalhes bibliográficos
Main Authors: Green, Michael E., Rech, Jason C., Floreancig, Paul E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3440178/
https://ncbi.nlm.nih.gov/pubmed/18683833
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.200802548
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