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Total Synthesis of Theopederin D

The total synthesis of the potent cytotoxin theopederin D has been achieved through the use of an oxidative carbon–carbon bond cleavage reaction to form an acyliminium ion in the presence of acid labile acetal groups Other key transformations include an acid mediated functionalization of a tetrahydr...

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Détails bibliographiques
Auteurs principaux: Green, Michael E., Rech, Jason C., Floreancig, Paul E.
Format: Artigo
Langue:Inglês
Publié: 2008
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3440178/
https://ncbi.nlm.nih.gov/pubmed/18683833
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.200802548
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