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Topoisomerase II is required for the production of long Pol II gene transcripts in yeast

The extent to which the DNA relaxation activities of eukaryotic topoisomerases (topo I and topo II) are redundant during gene transcription is unclear. Although both enzymes can often substitute for each other in vivo, studies in vitro had revealed that the DNA cross-inversion mechanism of topo II r...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Joshi, Ricky S., Piña, Benjamin, Roca, Joaquim
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3439932/
https://ncbi.nlm.nih.gov/pubmed/22718977
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks626
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