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Genome-wide localization and expression profiling establish Sp2 as a sequence-specific transcription factor regulating vitally important genes

The transcription factor Sp2 is essential for early mouse development and for proliferation of mouse embryonic fibroblasts in culture. Yet its mechanisms of action and its target genes are largely unknown. In this study, we have combined RNA interference, in vitro DNA binding, chromatin immunoprecip...

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Bibliografske podrobnosti
Main Authors: Terrados, Gloria, Finkernagel, Florian, Stielow, Bastian, Sadic, Dennis, Neubert, Juliane, Herdt, Olga, Krause, Michael, Scharfe, Maren, Jarek, Michael, Suske, Guntram
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2012
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3439921/
https://ncbi.nlm.nih.gov/pubmed/22684502
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks544
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