The ubiquitin E3 ligase WWP1 decreases CXCL12-mediated MDA231 breast cancer cell migration and bone metastasis()

Advanced breast cancers preferentially metastasize to bone where cells in the bone microenvironment produce factors that enhance breast cancer cell homing and growth. Expression of the ubiquitin E3 ligase WWP1 is increased in some breast cancers, but its role in bone metastasis has not been investig...

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Main Authors: Subik, Kristina, Shu, Lei, Wu, Chengyu, Liang, Qianqian, Hicks, David, Boyce, Brendan, Schiffhauer, Linda, Chen, Di, Chen, Ceshi, Tang, Ping, Xing, Lianping
Format: Artigo
Sprog:Inglês
Udgivet: 2012
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3439807/
https://ncbi.nlm.nih.gov/pubmed/22266093
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bone.2011.12.022
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