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Simplifying complex sequence information: a PCP-consensus protein binds antibodies against all four Dengue serotypes
Designing proteins that reflect the natural variability of a pathogen is essential for developing novel vaccines and drugs. Flaviviruses, including Dengue (DENV) and West Nile (WNV), evolve rapidly and can “escape” neutralizing monoclonal antibodies by mutation. Designing antigens that represent man...
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| Huvudupphovsmän: | , , , |
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| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
2012
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3439202/ https://ncbi.nlm.nih.gov/pubmed/22863657 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2012.07.042 |
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