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PCP-consensus sequences of Flaviviruses: correlating variance with vector competence and disease phenotype

BACKGROUND: Computational methods are needed to design multivalent vaccines against flaviviruses such as West Nile (WNV) or Dengue (DENV). OBJECTIVE: To use physico-chemical property consensus (PCP-consensus) sequences of Flavivirus strains to delineate conserved motifs, areas of maximum variability...

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Detalhes bibliográficos
Main Authors: Danecek, Petr, Lu, Wenzhe, Schein, Catherine H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2822003/
https://ncbi.nlm.nih.gov/pubmed/19969003
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2009.11.070
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