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A potent neutralizing antibody with therapeutic potential against all four serotypes of dengue virus
A therapy for dengue is still elusive. We describe the neutralizing and protective capacity of a dengue serotype-cross-reactive antibody isolated from the plasmablasts of a patient. Antibody SIgN-3C neutralized all four dengue virus serotypes at nano to picomolar concentrations and significantly dec...
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| Udgivet i: | NPJ Vaccines |
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| Main Authors: | , , , , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Publishing Group UK
2017
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5627287/ https://ncbi.nlm.nih.gov/pubmed/29263863 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41541-016-0003-3 |
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