Decrease in Fas-induced apoptosis by the γ-secretase inhibitor is dependent on p75(NTR) in a glioblastoma cell line

p75(NTR), a member of the tumor necrosis factor superfamily, plays a key role in numerous physiological processes, including cell survival or apoptosis. Yet, the associated signaling pathways remain poorly understood. Similar to Notch, γ-secretase cleavage is implicated in the p75(NTR) signaling pat...

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Main Authors: BESSETTE, BARBARA, DURAND, KARINE, GIRAUD, STÉPHANIE, BÉGAUD, GAËLLE, MATHONNET, MURIEL, LALLOUÉ, FABRICE
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2012
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3438831/
https://ncbi.nlm.nih.gov/pubmed/22969985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/etm.2012.480
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