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Effect of GPE-AGT nanoparticle shRNA transfection system mediated RNAi on early atherosclerotic lesion

OBJECTIVE: To investigate the effects of RNA interference targeting AGT on early atherosclerotic lesion in the hypertensive state. METHODS: Hypertension and atherosclerosis rats were treated with GPE nanoparticles carrying AGT shRNA. Systolic blood pressure and heart rate were measured for 2 consecu...

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Библиографические подробности
Главные авторы: Lu, Ping, Yuan, Lifen, Wang, Yuqiang, Du, Qin, Sheng, Jing
Формат: Artigo
Язык:Inglês
Опубликовано: e-Century Publishing Corporation 2012
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3438761/
https://ncbi.nlm.nih.gov/pubmed/22977667
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