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The role of PML ubiquitination in human malignancies

Tumor suppressors are frequently downregulated in human cancers and understanding of the mechanisms through which tumor cells restrict the expression of tumor suppressors is important for the prognosis and intervention of diseases. The promyelocytic leukemia (PML) protein plays a critical role in mu...

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Detalhes bibliográficos
Main Authors: Chen, Ruey-Hwa, Lee, Yu-Ru, Yuan, Wei-Chien
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3438505/
https://ncbi.nlm.nih.gov/pubmed/22935031
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1423-0127-19-81
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