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The role of autophagy in the pathogenesis of glycogen storage disease type II (GSDII)
Regulated removal of proteins and organelles by autophagy–lysosome system is critical for muscle homeostasis. Excessive activation of autophagy-dependent degradation contributes to muscle atrophy and cachexia. Conversely, inhibition of autophagy causes accumulation of protein aggregates and abnormal...
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| Главные авторы: | , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Nature Publishing Group
2012
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3438501/ https://ncbi.nlm.nih.gov/pubmed/22595755 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2012.52 |
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