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Impaired autophagy contributes to muscle atrophy in glycogen storage disease type II patients

The autophagy-lysosome system is essential for muscle cell homeostasis and its dysfunction has been linked to muscle disorders that are typically distinguished by massive autophagic buildup. Among them, glycogen storage disease type II (GSDII) is characterized by the presence of large glycogen-fille...

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Detalhes bibliográficos
Principais autores: Nascimbeni, Anna Chiara, Fanin, Marina, Masiero, Eva, Angelini, Corrado, Sandri, Marco
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3494606/
https://ncbi.nlm.nih.gov/pubmed/22940840
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/auto.21691
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