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Impaired autophagy contributes to muscle atrophy in glycogen storage disease type II patients
The autophagy-lysosome system is essential for muscle cell homeostasis and its dysfunction has been linked to muscle disorders that are typically distinguished by massive autophagic buildup. Among them, glycogen storage disease type II (GSDII) is characterized by the presence of large glycogen-fille...
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Principais autores: | , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Landes Bioscience
2012
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3494606/ https://ncbi.nlm.nih.gov/pubmed/22940840 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/auto.21691 |
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