Evidence for the Ubiquitin Protease UBP43 as an Antineoplastic Target

New pharmacologic targets are needed for lung cancer. One candidate pathway to target is composed of the E1-like ubiquitin-activating enzyme (UBE1L) that associates with interferon-stimulated gene 15 (ISG15), which complexes with and destabilizes cyclin D1. Ubiquitin protease 43 (UBP43/USP18) remove...

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Detalhes bibliográficos
Main Authors: Guo, Yongli, Chinyengetere, Fadzai, Dolinko, Andrey V., Lopez-Aguiar, Alexandra, Lu, Yun, Galimberti, Fabrizio, Ma, Tian, Feng, Qing, Sekula, David, Freemantle, Sarah, Andrew, Angeline S., Memoli, Vincent, Dmitrovsky, Ethan
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3438286/
https://ncbi.nlm.nih.gov/pubmed/22752428
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-12-0248
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