Abnormalities of Calcium Handling Proteins in Skeletal Muscle Mirror those of the Heart in Humans with Heart Failure: a Shared Mechanism?

BACKGROUND: In the failing human heart, abnormalities of Ca(2+) cycling have been described, but there is scant knowledge about Ca(2+) handling in the skeletal muscle of humans with HF. We tested the hypothesis that in humans with HF, Ca(2+) cycling proteins in skeletal muscle are abnormal. METHODS...

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Main Authors: Middlekauff, Holly R., Vigna, Chris, Verity, M. Anthony, Fonarow, Gregg C., Horwich, Tamara B., Hamilton, Michele A., Shieh, Perry, Tupling, A. Russell
Format: Artigo
Sprog:Inglês
Udgivet: 2012
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3437990/
https://ncbi.nlm.nih.gov/pubmed/22939042
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cardfail.2012.07.005
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