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Intact Skeletal Muscle Mitochondrial Enzyme Activity but Diminished Exercise Capacity in Advanced Heart Failure Patients on Optimal Medical and Device Therapy

BACKGROUND: A skeletal myopathy, perhaps attributable to neuro-endocrine excitation or disuse, has been described in heart failure (HF) patients, and is thought to contribute to their exercise limitation. Our purpose was to assess biochemical and morphometric characteristics of skeletal muscles of H...

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Detalhes bibliográficos
Main Authors: Middlekauff, Holly R., Verity, M. Anthony, Horwich, Tamara B., Fonarow, Gregg C., Hamilton, Michele A., Shieh, Perry
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3710307/
https://ncbi.nlm.nih.gov/pubmed/23575739
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00392-013-0564-3
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