Akt Inhibits Apoptosis Downstream of BID Cleavage via a Glucose-Dependent Mechanism Involving Mitochondrial Hexokinases

The serine/threonine kinase Akt/protein kinase B inhibits apoptosis induced by a variety of stimuli, including overexpression or activation of proapoptotic Bcl-2 family members. The precise mechanisms by which Akt prevents apoptosis are not completely understood, but Akt may function to maintain mit...

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Pubblicato in:	Mol Cell Biol
Autori principali:	Majewski, Nathan, Nogueira, Veronique, Robey, R. Brooks, Hay, Nissim
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Taylor & Francis 2004
Soggetti:	Cell Growth and Development
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC343797/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14701745/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.24.2.730-740.2004
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