EMILIN-1 Deficiency Induces Elastogenesis and Vascular Cell Defects

EMILINs constitute a family of genes of the extracellular matrix with high structural similarity. Four genes have been identified so far in human and mouse. To gain insight into the function of this gene family, EMILIN-1 has been inactivated in the mouse by gene targeting. The homozygous animals wer...

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Bibliographische Detailangaben
Hauptverfasser: Zanetti, Miriam, Braghetta, Paola, Sabatelli, Patrizia, Mura, Isabella, Doliana, Roberto, Colombatti, Alfonso, Volpin, Dino, Bonaldo, Paolo, Bressan, Giorgio M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2004
Schlagworte:
Mammalian Genetic Models with Minimal or Complex Phenotypes
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC343785/
https://ncbi.nlm.nih.gov/pubmed/14701737
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.2.638-650.2004
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