Identification of two functionally redundant RNA elements in the coding sequence of poliovirus using computer-generated design

Genomes of RNA viruses contain multiple functional RNA elements required for translation or RNA replication. We use unique approaches to identify functional RNA elements in the coding sequence of poliovirus (PV), a plus strand RNA virus. The general method is to recode large segments of the genome u...

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Autores principales: Song, Yutong, Liu, Ying, Ward, Charles B., Mueller, Steffen, Futcher, Bruce, Skiena, Steven, Paul, Aniko V., Wimmer, Eckard
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2012
Materias:
Biological Sciences
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3437848/
https://ncbi.nlm.nih.gov/pubmed/22886087
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1211484109
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