Identification of two functionally redundant RNA elements in the coding sequence of poliovirus using computer-generated design

Genomes of RNA viruses contain multiple functional RNA elements required for translation or RNA replication. We use unique approaches to identify functional RNA elements in the coding sequence of poliovirus (PV), a plus strand RNA virus. The general method is to recode large segments of the genome u...

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Bibliographic Details
Main Authors: Song, Yutong, Liu, Ying, Ward, Charles B., Mueller, Steffen, Futcher, Bruce, Skiena, Steven, Paul, Aniko V., Wimmer, Eckard
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2012
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3437848/
https://ncbi.nlm.nih.gov/pubmed/22886087
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1211484109
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