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High-content live-cell imaging assay used to establish mechanism of trastuzumab emtansine (T-DM1)–mediated inhibition of platelet production

Proplatelet production represents a terminal stage of megakaryocyte development during which long, branching processes composed of platelet-sized swellings are extended and released into the surrounding culture. Whereas the cytoskeletal mechanics driving these transformations have been the focus of...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Thon, Jonathan N., Devine, Matthew T., Jurak Begonja, Antonija, Tibbitts, Jay, Italiano, Joseph E.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society of Hematology 2012
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3437592/
https://ncbi.nlm.nih.gov/pubmed/22665936
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2012-04-420968
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