Enforced IL-10 Expression Confers Type 1 Regulatory T Cell (Tr1) Phenotype and Function to Human CD4(+) T Cells

Type 1 regulatory T (Tr1) cells are an inducible subset of CD4(+) Tr cells characterized by high levels of interleukin (IL)-10 production and regulatory properties. Several protocols to generate human Tr1 cells have been developed in vitro. However, the resulting population includes a significant fr...

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Main Authors: Andolfi, Grazia, Fousteri, Georgia, Rossetti, Maura, Magnani, Chiara F, Jofra, Tatiana, Locafaro, Grazia, Bondanza, Attilio, Gregori, Silvia, Roncarolo, Maria-Grazia
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2012
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Original Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3437582/
https://ncbi.nlm.nih.gov/pubmed/22692497
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2012.71
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