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Toxic effects of nicotinamide methylation on mouse brain striatum neuronal cells and its relation to manganese
OBJECTIVE: It is well known that manganese (Mn) exposure is involved in parkinsonism. The aim of our study was to test the hypotheses that Mn affects nicotinamide N-methyltransferase (NNMT) activity, increases the metabolism of nicotinamide (NA) to 1-methylnicotinamide (MNA), and leads to neurocytot...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Springer Japan
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3437358/ https://ncbi.nlm.nih.gov/pubmed/22249857 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12199-011-0262-6 |
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