EFFECT OF CYP2A6*4 GENETIC POLYMORPHISMS ON SMOKING BEHAVIORS AND NICOTINE DEPENDENCE IN A GENERAL POPULATION OF JAPANESE MEN

Objectives: Nicotine in cigarettes is metabolized primarily by CYP2A6-catalyzed oxidation. The CYP2A6*4 allele, in which CYP2A6 is a homozygous whole-deletion variant, completely lacks enzyme activity. The aim of this study was to examine the effects of CYP2A6*4 genetic polymorphism on smoking behav...

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Detalhes bibliográficos
Publicado no:Fukushima J Med Sci
Main Authors: ITO, TERUNA, TSUJI, MASAYOSHI, MORI, YAYOI, KANDA, HIDEYUKI, HIDAKA, TOMOO, KAKAMU, TAKEYASU, KUMAGAI, TOMOHIRO, HAYAKAWA, TAKEHITO, OSAKI, YONEATSU, FUKUSHIMA, TETSUHITO
Formato: Artigo
Idioma:Inglês
Publicado em: The Fukushima Society of Medical Science 2015
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5131587/
https://ncbi.nlm.nih.gov/pubmed/26370685
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5387/fms.2015-14
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