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Apoptosis Signal-Regulating Kinase 1–Thioredoxin Complex Dissociation by Capsaicin Causes Pancreatic Tumor Growth Suppression by Inducing Apoptosis
Aim: In this study, we evaluated the effect of capsaicin on the interaction of redox-sensitive thioredoxin (Trx)/apoptosis signal-regulating kinase 1 (ASK1) in pancreatic cancer cells. Results: Capsaicin treatment downregulated Trx and increased the phosphorylation (activation) of ASK1 at Thr845 and...
Tallennettuna:
| Päätekijät: | , |
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| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
Mary Ann Liebert, Inc.
2012
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3437051/ https://ncbi.nlm.nih.gov/pubmed/22530568 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/ars.2011.4369 |
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