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Penfluridol suppresses pancreatic tumor growth by autophagy-mediated apoptosis

Pancreatic tumors exhibit enhanced autophagy as compared to any other cancer, making it resistant to chemotherapy. We evaluated the effect of penfluridol against pancreatic cancer. Penfluridol treatment induced apoptosis and inhibited the growth of Panc-1, BxPC-3 and AsPC-1, pancreatic cancer cells...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Ranjan, Alok, Srivastava, Sanjay K.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4870635/
https://ncbi.nlm.nih.gov/pubmed/27189859
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep26165
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