Chargement en cours...
Penfluridol suppresses glioblastoma tumor growth by Akt-mediated inhibition of GLI1
Glioblastoma (GBM) is the most common brain tumor with poor survival rate. Our results show that penfluridol, an antipsychotic drug significantly reduced the survival of ten adult and pediatric glioblastoma cell lines with IC(50) ranging 2–5 μM after 72 hours of treatment and induced apoptosis. Penf...
Enregistré dans:
| Publié dans: | Oncotarget |
|---|---|
| Auteurs principaux: | , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Impact Journals LLC
2017
|
| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5464842/ https://ncbi.nlm.nih.gov/pubmed/28380428 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.16515 |
| Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|