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Natural IgM mediates complement-dependent uptake of Francisella tularensis by human neutrophils via CR1 and CR3 in nonimmune serum

A fundamental step in the life cycle of F. tularensis is bacterial entry into host cells. F. tularensis activates complement, and recent data suggest that the classical pathway is required for complement factor C3 deposition on the bacterial surface. Nevertheless, C3 deposition is inefficient and ne...

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Detaylı Bibliyografya
Asıl Yazarlar: Schwartz, Justin T., Barker, Jason H., Long, Matthew E., Kaufman, Justin, McCracken, Jenna, Allen, Lee-Ann H.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2012
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3436988/
https://ncbi.nlm.nih.gov/pubmed/22888138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1200816
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