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Francisella tularensis inhibits the intrinsic and extrinsic pathways to delay constitutive apoptosis and prolong human neutrophil lifespan()

Francisella tularensis is a facultative intracellular bacterium that infects many cell types including neutrophils. We demonstrated previously that F. tularensis inhibits NADPH oxidase assembly and activity and then escapes the phagosome to the cytosol, but effects on other aspects of neutrophil fun...

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Hlavní autoři: Schwartz, Justin T., Barker, Jason H., Kaufman, Justin, Fayram, Drew C., McCracken, Jenna M., Allen, Lee-Ann H.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3311780/
https://ncbi.nlm.nih.gov/pubmed/22357630
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1102863
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