Early Secreted Antigenic Target of 6- kD Protein of Mycobacterium tuberculosis Primes Dendritic Cells to Stimulate Th17 and Inhibit Th1 Immune Responses

Early secreted antigenic target of 6 kD (ESAT-6) of Mycobacterium tuberculosis is a T-cell antigen that is a potential vaccine candidate, but it is also a virulence factor that mediates pathogenicity. To better understand the effects of ESAT-6 on the immune response, we studied the effect of ESAT-6...

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Detalhes bibliográficos
Main Authors: Wang, Xisheng, Barnes, Peter F., Huang, Fangfang, Alvarez, Ivana B., Neuenschwander, Pierre F., Sherman, David R., Samten, Buka
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3436987/
https://ncbi.nlm.nih.gov/pubmed/22904313
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1200573
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