CD5-dependent CK2 activation pathway regulates threshold for T-cell anergy()

CD5 activates CK2, a serine/threonine kinase that constitutively associates with the CK2-binding domain at the end of its cytoplasmic tail. To determine the physiological significance of CD5-dependent CK2 activation in T-cells we generated a knock-in mouse that expresses a CD5 protein containing a m...

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Detaylı Bibliyografya
Asıl Yazarlar: Sestero, Christine M., McGuire, Donald J., De Sarno, Patrizia, Brantley, Emily C., Soldevila, Gloria, Axtell, Robert C., Raman, Chander
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2012
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3436980/
https://ncbi.nlm.nih.gov/pubmed/22904299
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1200065
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