Creating and analyzing pathway and protein interaction compendia for modelling signal transduction networks

BACKGROUND: Understanding the information-processing capabilities of signal transduction networks, how those networks are disrupted in disease, and rationally designing therapies to manipulate diseased states require systematic and accurate reconstruction of network topology. Data on networks centra...

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Autors principals: Kirouac, Daniel C, Saez-Rodriguez, Julio, Swantek, Jennifer, Burke, John M, Lauffenburger, Douglas A, Sorger, Peter K
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2012
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3436686/
https://ncbi.nlm.nih.gov/pubmed/22548703
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1752-0509-6-29
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