Dynamin-mediated Nephrin Phosphorylation Regulates Glucose-stimulated Insulin Release in Pancreatic Beta Cells

We have previously demonstrated a role for Nephrin in glucose stimulated insulin release (GSIR). We now hypothesize that Nephrin phosphorylation is required for GSIR and that Dynamin influences Nephrin phosphorylation and function. MIN6-C3 Nephrin-deficient pancreatic beta cells and human islets wer...

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Detaylı Bibliyografya
Asıl Yazarlar: Jeon, Jongmin, Leibiger, Ingo, Moede, Tilo, Walter, Britta, Faul, Christian, Maiguel, Dony, Villarreal, Rodrigo, Guzman, Johanna, Berggren, Per-Olof, Mundel, Peter, Ricordi, Camillo, Merscher-Gomez, Sandra, Fornoni, Alessia
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Biochemistry and Molecular Biology 2012
Konular:
Cell Biology
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3436561/
https://ncbi.nlm.nih.gov/pubmed/22718751
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.389452
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