Nephrin Contributes to Insulin Secretion and Affects Mammalian Target of Rapamycin Signaling Independently of Insulin Receptor

Nephrin belongs to a family of highly conserved proteins with a well characterized function as modulators of cell adhesion and guidance, and nephrin may have a role in metabolic pathways linked to podocyte and pancreatic β–cell survival. However, this role is incompletely characterized. In this stud...

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Vydáno v:J Am Soc Nephrol
Hlavní autoři: Villarreal, Rodrigo, Mitrofanova, Alla, Maiguel, Dony, Morales, Ximena, Jeon, Jongmin, Grahammer, Florian, Leibiger, Ingo B., Guzman, Johanna, Fachado, Alberto, Yoo, Tae H., Busher Katin, Anja, Gellermann, Jutta, Merscher, Sandra, Burke, George W., Berggren, Per-Olof, Oh, Jun, Huber, Tobias B., Fornoni, Alessia
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society of Nephrology 2016
Témata:
Basic Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4814188/
https://ncbi.nlm.nih.gov/pubmed/26400569
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2015020210
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