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Diindolylmethane-mediated Gli1 Protein Suppression Induces Anoikis in Ovarian Cancer Cells in Vitro and Blocks Tumor Formation Ability in Vivo

Anoikis is a cell death that occurs due to detachment of a cell from the extracellular matrix (ECM). Resistance to anoikis is a primary feature of a cell that undergoes metastasis. In this study for the first time, we demonstrated the potential role of Gli1 in anoikis resistance. Treatment of variou...

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Main Authors: Kandala, Prabodh K., Srivastava, Sanjay K.
格式: Artigo
語言:Inglês
出版: American Society for Biochemistry and Molecular Biology 2012
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3436512/
https://ncbi.nlm.nih.gov/pubmed/22773833
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.351379
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