Diindolylmethane suppresses ovarian cancer growth and potentiates the effect of cisplatin in tumor mouse model by targeting signal transducer and activator of transcription 3 (STAT3)

<p>Abstract</p> <p>Background</p> <p>Signal transducer and activator of transcription 3 (STAT3) is activated in majority of ovarian tumors and confers resistance to cisplatin treatment in patients with ovarian cancer. We have reported previously that diindolylmethane (D...

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Détails bibliographiques
Auteurs principaux: Kandala Prabodh K, Srivastava Sanjay K
Format: Artigo
Langue:Inglês
Publié: BMC 2012-01-01
Collection:BMC Medicine
Sujets:
apoptosis
angiogenesis
cisplatin
diindolylmethane
STAT3
Accès en ligne:http://www.biomedcentral.com/1741-7015/10/9
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