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Antitumor activity of erlotinib in combination with gemcitabine in in vitro and in vivo models of KRAS-mutated pancreatic cancers

Erlotinib treatment in combination with gemcitabine is a standard therapy for patients with locally advanced pancreatic cancer in many countries, including the US and the EU. Since mutations of the K-ras oncogene (KRAS) occur in approximately 90% of pancreatic cancers, we examined the antitumor acti...

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Bibliografski detalji
Glavni autori: FURUGAKI, KOH, IWAI, TOSHIKI, KONDOH, KUMIKO, MORIYA, YOICHIRO, MORI, KAZUSHIGE
Format: Artigo
Jezik:Inglês
Izdano: D.A. Spandidos 2010
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3436476/
https://ncbi.nlm.nih.gov/pubmed/22966286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol_00000041
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