Erlotinib inhibits osteolytic bone invasion of human non-small-cell lung cancer cell line NCI-H292

Previous preclinical and clinical findings have suggested a potential role of epidermal growth factor receptor (EGFR) in osteoclast differentiation and the pathogenesis of bone metastasis in cancer. In this study, we investigated the effect of erlotinib, an orally active EGFR tyrosine kinase inhibit...

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Autores principales: Furugaki, Koh, Moriya, Yoichiro, Iwai, Toshiki, Yorozu, Keigo, Yanagisawa, Mieko, Kondoh, Kumiko, Fujimoto-Ohuchi, Kaori, Mori, Kazushige
Formato: Artigo
Lenguaje:Inglês
Publicado: Springer Netherlands 2011
Materias:
Research Paper
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3198194/
https://ncbi.nlm.nih.gov/pubmed/21688034
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10585-011-9398-4
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