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Bevacizumab counteracts VEGF-dependent resistance to erlotinib in an EGFR-mutated NSCLC xenograft model
Erlotinib, an epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor (TKI), shows superior efficacy in patients with non-small cell lung cancer (NSCLC) harboring activating EGFR mutations (EGFR Mut(+)). However, almost all tumors eventually develop resistance to erlotinib. Recently, the P...
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| Udgivet i: | Int J Oncol |
|---|---|
| Main Authors: | , , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
D.A. Spandidos
2017
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5504975/ https://ncbi.nlm.nih.gov/pubmed/28627678 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ijo.2017.4036 |
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