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A Generic Crystallization-like Model That Describes the Kinetics of Amyloid Fibril Formation

Associated with neurodegenerative disorders such as Alzheimer, Parkinson, or prion diseases, the conversion of soluble proteins into amyloid fibrils remains poorly understood. Extensive “in vitro” measurements of protein aggregation kinetics have been reported, but no consensus mechanism has emerged...

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Detalhes bibliográficos
Main Authors: Crespo, Rosa, Rocha, Fernando A., Damas, Ana M., Martins, Pedro M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3436372/
https://ncbi.nlm.nih.gov/pubmed/22767606
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.375345
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