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Characterization of a Proteasome and TAP-independent Presentation of Intracellular Epitopes by HLA-B27 Molecules

Nascent HLA-class I molecules are stabilized by proteasome-derived peptides in the ER and the new complexes proceed to the cell surface through the post-ER vesicles. It has been shown, however, that less stable complexes can exchange peptides in the Trans Golgi Network (TGN). HLA-B27 are the most st...

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Detalhes bibliográficos
Main Authors: Magnacca, Adriana, Persiconi, Irene, Nurzia, Elisa, Caristi, Silvana, Meloni, Francesca, Barnaba, Vincenzo, Paladini, Fabiana, Raimondo, Domenico, Fiorillo, Maria Teresa, Sorrentino, Rosa
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3436287/
https://ncbi.nlm.nih.gov/pubmed/22807446
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.384339
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