Cathepsin B Is Secreted Apically from Xenopus 2F3 Cells and Cleaves the Epithelial Sodium Channel (ENaC) to Increase Its Activity

The epithelial sodium channel (ENaC) plays an important role in regulating sodium balance, extracellular volume, and blood pressure. Evidence suggests the α and γ subunits of ENaC are cleaved during assembly before they are inserted into the apical membranes of epithelial cells, and maximal activity...

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Detaylı Bibliyografya
Asıl Yazarlar: Alli, Abdel A., Song, John Z., Al-Khalili, Otor, Bao, Hui-Fang, Ma, He-Ping, Alli, Alia A., Eaton, Douglas C.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Biochemistry and Molecular Biology 2012
Konular:
Signal Transduction
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3436264/
https://ncbi.nlm.nih.gov/pubmed/22782900
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.338574
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