Human microRNA-1245 down-regulates the NKG2D receptor in natural killer cells and impairs NKG2D-mediated functions

BACKGROUND: NKG2D is an activating receptor expressed by natural killer and T cells, which have crucial functions in tumor and microbial immunosurveillance. Several cytokines have been identified as modulators of NKG2D receptor expression. However, little is known about NKG2D gene regulation. In thi...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Espinoza, J. Luis, Takami, Akiyoshi, Yoshioka, Katsuji, Nakata, Katsuya, Sato, Tokiharu, Kasahara, Yoshihito, Nakao, Shinji
Médium: Artigo
Jazyk:Inglês
Vydáno: Ferrata Storti Foundation 2012
Témata:
Original Articles and Brief Reports
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3436229/
https://ncbi.nlm.nih.gov/pubmed/22491735
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2011.058529
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky