The Drosophila Neurally Altered Carbohydrate Mutant Has a Defective Golgi GDP-fucose Transporter

Studying genetic disorders in model organisms can provide insights into heritable human diseases. The Drosophila neurally altered carbohydrate (nac) mutant is deficient for neural expression of the HRP epitope, which consists of N-glycans with core α1,3-linked fucose residues. Here, we show that a c...

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Main Authors: Geisler, Christoph, Kotu, Varshika, Sharrow, Mary, Rendić, Dubravko, Pöltl, Gerald, Tiemeyer, Michael, Wilson, Iain B. H., Jarvis, Donald L.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2012
Teme:
Glycobiology and Extracellular Matrices
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3436151/
https://ncbi.nlm.nih.gov/pubmed/22745127
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.379313
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