The Drosophila Neurally Altered Carbohydrate Mutant Has a Defective Golgi GDP-fucose Transporter

Studying genetic disorders in model organisms can provide insights into heritable human diseases. The Drosophila neurally altered carbohydrate (nac) mutant is deficient for neural expression of the HRP epitope, which consists of N-glycans with core α1,3-linked fucose residues. Here, we show that a c...

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Bibliografiske detaljer
Main Authors: Geisler, Christoph, Kotu, Varshika, Sharrow, Mary, Rendić, Dubravko, Pöltl, Gerald, Tiemeyer, Michael, Wilson, Iain B. H., Jarvis, Donald L.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2012
Fag:
Glycobiology and Extracellular Matrices
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3436151/
https://ncbi.nlm.nih.gov/pubmed/22745127
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.379313
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