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The Drosophila Neurally Altered Carbohydrate Mutant Has a Defective Golgi GDP-fucose Transporter

Studying genetic disorders in model organisms can provide insights into heritable human diseases. The Drosophila neurally altered carbohydrate (nac) mutant is deficient for neural expression of the HRP epitope, which consists of N-glycans with core α1,3-linked fucose residues. Here, we show that a c...

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Detalhes bibliográficos
Main Authors: Geisler, Christoph, Kotu, Varshika, Sharrow, Mary, Rendić, Dubravko, Pöltl, Gerald, Tiemeyer, Michael, Wilson, Iain B. H., Jarvis, Donald L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3436151/
https://ncbi.nlm.nih.gov/pubmed/22745127
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.379313
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